Does PharmGenetix also offer genetic counseling?
Your doctor is our partner. PharmGenetix offers only analysis and results. Always consult with your physician.
Will the results tell me whether I am at risk of developing certain diseases?
We focus on medication. The analyses offered by PharmGenetix currently include pharmacogenetic trials – which test the efficacy of medications. If a predictive statement can be made based on the analyses, your doctor can discuss this with you.
Can I also have samples from other people analysed?
No. The consent of the person concerned is required for an analysis. The doctor’s signature also confirms that the blood sample and the signature have come from the same person.
Minors and persons to whom a guardian has been assigned are exempt. In this case, the consent declaration must be submitted by a guardian or person with parental authority.
If you let others know about the advantages of genetic analysis for optimization of individual treatments, please refer the interested persons to our website (www.pharmgenetix.com).
What happens to my sample after the analysis?
With your consent, your blood sample can be stored in our partner laboratories. Since research in the area of pharmacogenetics is never at a standstill, new mutations are constantly being discovered. PharmGenetix would like to always keep you up-to-date! Approximately every one to two years, you can have PharmGenetix re-test your already available blood sample for new, pharmacogenetic relevant SNPs. PharmGenetix will remind you when this time comes.
If you do not wish to take advantage of this service, you can of course opt out of having your sample kept when you sign your consent form. In this case, your sample will be destroyed after the analysis you ordered is complete.
What distinguishes PharmGenetix from other genetic analysis providers?
A comparison is valid only when like is compared with like. So be careful, since only a few mutations are tested by other providers. With our PGx panel, we test more than 160 mutations that play a central role in the compatibility of medications (this PGx panel is continually adapted to new scientific findings). In addition, we offer a “comprehensive” analysis of CYP2D6, which is the most detailed, in-depth analysis of CYP2D6 available in Europe.
In addition to the number of tested mutations, the quality of the analysis is also crucial. PharmGenetix applies internationally leading quality standards; the analysis is therefore carried out on two different platforms, physically and chemically independent from each other. You can always rely on our quality standards! For more information about this CYP2D6 analysis, please contact us directly.
What is tested?
Genes are sections of DNA, the carrier of our genetic information. Everyone has a unique assemblage of DNA – i.e. an individual genetic blueprint. This blueprint of life is created at conception: chromosomes from the mother and chromosomes from the father exchange small pieces of their genetic information (chromosomal recombination).
Chromosomes are thus passed onto the next generation, which represent a mixture of the genetic material from both parents. This creates new combinations of characteristics and allows for great genetic diversity. During this DNA mixing, different chromosome exchange processes occur.
Through this process, genetic information can, however, be lost, copied several times or additionally modified at selective points. These changes in DNA are called mutations, which can have both good and bad effects. They are a decisive factor in evolution, and the starting point for the transformation and adaptation of living beings to their environment.
Active drug ingredients are absorbed in our body, transported to the right places, converted and excreted. A very complex enzyme system is responsible for all these steps. Since enzymes differ from person to person, they can occur in forms that differ from each other in varying degrees, from slight to extreme. Therefore, we humans may react completely differently to identical medications and absorb them more quickly or slowly, break them down faster or slower, or eliminate the active substances (or their degradation products) more quickly or more slowly.
If active ingredients from medications are broken down more rapidly or more slowly, there is a clear fluctuation in the concentration of active substances in the blood, thus leading to the occurrence of side effects or loss of effectiveness.
What ethical values do PharmGenetix practice?
We are of the opinion that every person has the right to personalized medical treatment that is up to date with the latest research!
Our analyses are only performed after receiving the patient’s written consent. The analysis results and the findings are also your property, meaning only you decide who is able to access your data. Personalized medicine also means individual responsibility in dealing with your own health data.
Furthermore, data protection and ensuring privacy are very important to us. Patient results can be stored at the highest safety level in the patient’s E-Safe at our IT partner, the Austrian company A-Trust. In the laboratory, the analysis result is ONLY stored anonymously, so that there is NO electronic link between the analysis result and the patient.
What is the medical value of my results?
The PharmGenetix result has a very high, fundamental medical value: only through a precise analysis of your DNA blueprint can you ensure that your medications are individually adapted to your genetic profile. The results we provide help your doctor customize your medication to your needs, which leads to maximum benefit and minimal side effects.
Are the analyses performed anonymously?
Yes. As soon as we have received your written consent and blood sample in the laboratory, the analysis is carried out exclusively by means of anonymized coding.
Where are the analyses performed?
PharmGenetix works exclusively with certified laboratories that meet all requirements for GLP (Good Laboratory Practices) and have the necessary accreditation with national agencies and/or ministries (drug and medicine regulatory agencies, etc.).
Analyses for our Austrian customers are conducted exclusively by one of the world’s leading laboratories, PharmGenetix’s own laboratory in Niederalm-Anif, Salzburg. (See partner laboratories.)